Side Effects Game

Welcome to Pill Roulette – Where Survival Is Not Guaranteed

In Side Effects Game, you’re trapped in a bleak experimental trial. Two test subjects sit across from each other. Only one will walk away. There’s no room for luck alone—you’ll need wit, strategy, and iron nerves to survive.

Each round is a gamble with your life. You take pills, not knowing whether they’ll heal you, harm you, or send you spiraling into madness. Along the way, you’ll use items to manipulate the odds, but be warned: the deeper you go, the higher your tolerance, and the deadlier each dose becomes.

A Battle of Minds, Not Just Reflexes

Unlike traditional horror games that rely on jump scares or fast action, Side Effects Game thrives on tension. It’s quiet. Clinical. Cold. And every decision counts. You're constantly calculating risks, analyzing your opponent, and trying to keep your cool when the odds turn against you.

Core Features of Side Effects Game

• Take Pills at Your Own Risk – Will it be pain, power, or something worse?

• Use Strategic Items – Control the game with clever tools and tricks.

• Manage Tolerance – Each pill increases your resistance... and the danger.

• Two Enter, One Leaves – Face off in a deadly medical experiment.

• Backspace to Restart – Instant replayability for a fast, addictive experience.

• Best Played Downloaded – While playable in-browser, the full experience shines in the downloadable version, with improved visuals and performance.

Why Horror Fans Can’t Stop Talking About It

Side Effects Game doesn’t just scare you—it unnerves you. Its pixelated style and eerie atmosphere are deceptive; beneath the simple visuals lies a disturbingly real sense of dread. It’s the kind of horror that creeps in slowly, then slams you with brutal outcomes you didn’t see coming.

Whether you’re a fan of minimalist horror, psychological tension, or high-stakes survival mechanics, this game delivers. And with each run being different, it’s endlessly replayable.

Think You Can Handle the Pressure?

There’s no escape. Only choices. Some pills help. Others destroy. Every move you make might save your life—or end it instantly. Side Effects Game offers a horror experience unlike anything else in the indie scene right now.

Download or play Side Effects Game today—and see if you’re strong enough to survive.